Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IL17A	HGNC:5981 (HGNC) 3605 (Entrez Gene) 603149 (OMIM) IL17A (Alliance of Genome Resources)	Chr6 p12.2	Chr6:52186375-52190638 (+) GRCh38	allergic rhinitis ankylosing spondylitis asthma bronchiolitis Graves' disease macular degeneration Mycobacterium avium complex disease psoriasis psoriatic arthritis rheumatoid arthritis rhinitis temporal arteritis	Q16552 (UniProt | EBI) NM_002190 (RefSeq)
mouse	Il17a	MGI:107364 (MGI) 16171 (Entrez Gene) Gene Tree Il17a (Alliance of Genome Resources)	Chr1 6.45 cM	Chr1:20801129-20804720 (+) GRCm39		16171 (NCBI Gene Model) Q62386 (UniProt | EBI) NM_010552 (RefSeq)
rat	Il17a	RGD:2888 (Rat Genome Database) 301289 (Entrez Gene) Il17a (Alliance of Genome Resources)	Chr9 q13			Q61453 (UniProt | EBI) NM_001106897 (RefSeq)
zebrafish	il17a/f3	ZDB-GENE-041001-192 (Zebrafish Model Organism Database) 553962 (Entrez Gene) il17a/f3 (Alliance of Genome Resources)	Chr20			NP_001018626 (RefSeq) NM_001020790 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.