Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FLNC	HGNC:3756 (HGNC) 2318 (Entrez Gene) 102565 (OMIM) FLNC (Alliance of Genome Resources)	Chr7 q32.1	Chr7:128830406-128859274 (+) GRCh38	distal myopathy 4 hypertrophic cardiomyopathy 26 myofibrillar myopathy 5	Q14315 (UniProt | EBI) NM_001458 (RefSeq)
mouse	Flnc	MGI:95557 (MGI) 68794 (Entrez Gene) Gene Tree Flnc (Alliance of Genome Resources)	Chr6 12.36 cM	Chr6:29433255-29461882 (+) GRCm39	myofibrillar myopathy 5	ENSMUSG00000068699 (Ensembl Gene Model) ENSMUSP00000064163 (Ensembl) ENSMUST00000065090 (Ensembl)
rat	Flnc	RGD:1308807 (Rat Genome Database) 362332 (Entrez Gene) Flnc (Alliance of Genome Resources)	Chr4 q22			D3ZHA0 (UniProt | EBI) NM_001191862 (RefSeq)
zebrafish	flnca	ZDB-GENE-070503-1 (Zebrafish Model Organism Database) 100048921 (Entrez Gene) flnca (Alliance of Genome Resources)	Chr25			XP_002666982 (RefSeq)
	flncb	ZDB-GENE-041008-175 (Zebrafish Model Organism Database) 570288 (Entrez Gene) flncb (Alliance of Genome Resources)	Chr4			XP_021330903 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.