Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	AFG1L	HGNC:16411 (HGNC) 246269 (Entrez Gene) 617469 (OMIM) AFG1L (Alliance of Genome Resources)	Chr6 q21	Chr6:108294991-108526796 (+) GRCh38		Q8WV93 (UniProt | EBI) NM_145315 (RefSeq)
mouse	Afg1l	MGI:2148801 (MGI) 215951 (Entrez Gene) Gene Tree Afg1l (Alliance of Genome Resources)	Chr10 22.88 cM	Chr10:42188581-42354561 (-) GRCm39		ENSMUSG00000038302 (Ensembl Gene Model) ENSMUSP00000036149 (Ensembl) ENSMUST00000041024 (Ensembl)
rat	Afg1l	RGD:1561501 (Rat Genome Database) 502479 (Entrez Gene) Afg1l (Alliance of Genome Resources)	Chr20 q13			Q32PX9 (UniProt | EBI) NM_001037656 (RefSeq)
zebrafish	afg1la	ZDB-GENE-091006-2 (Zebrafish Model Organism Database) 561238 (Entrez Gene) afg1la (Alliance of Genome Resources)	Chr17			NP_001186696 (RefSeq) NM_001199767 (RefSeq)
	afg1lb	ZDB-GENE-041014-178 (Zebrafish Model Organism Database) 555926 (Entrez Gene) afg1lb (Alliance of Genome Resources)	Chr20			Q5TYS0 (UniProt | EBI) NM_001025482 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.