Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ADCY3	HGNC:234 (HGNC) 109 (Entrez Gene) 600291 (OMIM) ADCY3 (Alliance of Genome Resources)	Chr2 p23.3	Chr2:24819169-24920237 (-) GRCh38		O60266 (UniProt | EBI) NM_001377131 (RefSeq)
mouse	Adcy3	MGI:99675 (MGI) 104111 (Entrez Gene) Gene Tree Adcy3 (Alliance of Genome Resources)	Chr12 1.99 cM	Chr12:4183397-4263525 (+) GRCm39	major depressive disorder	104111 (NCBI Gene Model) Q8VHH7 (UniProt | EBI) NM_001422786 (RefSeq)
rat	Adcy3	RGD:71009 (Rat Genome Database) 64508 (Entrez Gene) Adcy3 (Alliance of Genome Resources)	Chr6 q14			P21932 (UniProt | EBI) NM_130779 (RefSeq)
zebrafish	adcy3a	ZDB-GENE-111027-6 (Zebrafish Model Organism Database) 571825 (Entrez Gene) adcy3a (Alliance of Genome Resources)	Chr16			NP_001156014 (RefSeq) NM_001162542 (RefSeq)
	adcy3b	ZDB-GENE-041014-276 (Zebrafish Model Organism Database) 564719 (Entrez Gene) adcy3b (Alliance of Genome Resources)	Chr20			XP_068071803 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.