Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FLNB	HGNC:3755 (HGNC) 2317 (Entrez Gene) 603381 (OMIM) FLNB (Alliance of Genome Resources)	Chr3 p14.3	Chr3:58008398-58172251 (+) GRCh38	atelosteogenesis bone development disease Boomerang dysplasia cleft palate clubfoot Larsen syndrome osteochondrodysplasia spinal disease spondylocarpotarsal synostosis syndrome	O75369 (UniProt | EBI) NM_001164318 (RefSeq)
mouse	Flnb	MGI:2446089 (MGI) 286940 (Entrez Gene) Gene Tree Flnb (Alliance of Genome Resources)	Chr14 4.59 cM	Chr14:14518185-14651816 (-) GRCm39	spondylocarpotarsal synostosis syndrome	ENSMUSG00000025278 (Ensembl Gene Model) ENSMUSP00000052020 (Ensembl) ENSMUST00000052678 (Ensembl)
rat	Flnb	RGD:1311915 (Rat Genome Database) 306204 (Entrez Gene) Flnb (Alliance of Genome Resources)	Chr15 p14			NP_001418475 (RefSeq) NM_001431547 (RefSeq)
zebrafish	flnb	ZDB-GENE-041026-1 (Zebrafish Model Organism Database) 563023 (Entrez Gene) flnb (Alliance of Genome Resources)	Chr23			XP_021330211 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.