Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MYO5A	HGNC:7602 (HGNC) 4644 (Entrez Gene) 160777 (OMIM) MYO5A (Alliance of Genome Resources)	Chr15 q21.2	Chr15:52307281-52529132 (-) GRCh38	Griscelli syndrome type 1	Q9Y4I1 (UniProt | EBI) NM_001142495 (RefSeq)
mouse	Myo5a	MGI:105976 (MGI) 17918 (Entrez Gene) Gene Tree Myo5a (Alliance of Genome Resources)	Chr9 42.26 cM	Chr9:74978297-75130970 (+) GRCm39	Griscelli syndrome type 1	ENSMUSG00000034593 (Ensembl Gene Model) ENSMUSP00000117493 (Ensembl) ENSMUST00000155282 (Ensembl)
rat	Myo5a	RGD:3143 (Rat Genome Database) 25017 (Entrez Gene) Myo5a (Alliance of Genome Resources)	Chr8 q24			Q9QYF3 (UniProt | EBI) NM_022178 (RefSeq)
zebrafish	myo5aa	ZDB-GENE-041027-2 (Zebrafish Model Organism Database) 562188 (Entrez Gene) myo5aa (Alliance of Genome Resources)	Chr18			XP_021329007 (RefSeq) NM_001080959 (RefSeq)
	myo5ab	ZDB-GENE-050411-72 (Zebrafish Model Organism Database) 565267 (Entrez Gene) myo5ab (Alliance of Genome Resources)	Chr25			XP_068073588 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.