Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	E2F8	HGNC:24727 (HGNC) 79733 (Entrez Gene) 612047 (OMIM) E2F8 (Alliance of Genome Resources)	Chr11 p15.1	Chr11:19224063-19241655 (-) GRCh38		A0AVK6 (UniProt | EBI) NM_024680 (RefSeq)
mouse	E2f8	MGI:1922038 (MGI) 108961 (Entrez Gene) Gene Tree E2f8 (Alliance of Genome Resources)	Chr7 31.11 cM	Chr7:48516177-48531344 (-) GRCm39		ENSMUSG00000046179 (Ensembl Gene Model) ENSMUSP00000112883 (Ensembl) ENSMUST00000119223 (Ensembl)
rat	E2f8	RGD:1308091 (Rat Genome Database) 308607 (Entrez Gene) E2f8 (Alliance of Genome Resources)	Chr1 q22			F1LMN3 (UniProt | EBI) NM_001100580 (RefSeq)
zebrafish	e2f8	ZDB-GENE-041111-260 (Zebrafish Model Organism Database) 565952 (Entrez Gene) e2f8 (Alliance of Genome Resources)	Chr7			F1QZ88 (UniProt | EBI) NM_001347691 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.