Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	UBE3A	HGNC:12496 (HGNC) 7337 (Entrez Gene) 601623 (OMIM) UBE3A (Alliance of Genome Resources)	Chr15 q11.2	Chr15:25333728-25439056 (-) GRCh38	Angelman syndrome	Q05086 (UniProt | EBI) NM_130838 (RefSeq)
mouse	Ube3a	MGI:105098 (MGI) 22215 (Entrez Gene) Gene Tree Ube3a (Alliance of Genome Resources)	Chr7 33.95 cM	Chr7:58878498-58961284 (+) GRCm39	Angelman syndrome	ENSMUSG00000025326 (Ensembl Gene Model) ENSMUSP00000143859 (Ensembl) ENSMUST00000200758 (Ensembl)
rat	Ube3a	RGD:1306361 (Rat Genome Database) 361585 (Entrez Gene) Ube3a (Alliance of Genome Resources)	Chr1 q22			NP_001178766 (RefSeq) NM_001191837 (RefSeq)
zebrafish	ube3a	ZDB-GENE-041114-190 (Zebrafish Model Organism Database) 792398 (Entrez Gene) ube3a (Alliance of Genome Resources)	Chr6			NP_001007319 (RefSeq) NM_001007318 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.