Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MVK	HGNC:7530 (HGNC) 4598 (Entrez Gene) 251170 (OMIM) MVK (Alliance of Genome Resources)	Chr12 q24.11	Chr12:109573255-109598125 (+) GRCh38	hyperimmunoglobulinemia D periodic fever syndrome lipid metabolism disorder mevalonic aciduria porokeratosis	Q03426 (UniProt | EBI) NM_001414513 (RefSeq)
mouse	Mvk	MGI:107624 (MGI) 17855 (Entrez Gene) Gene Tree Mvk (Alliance of Genome Resources)	Chr5 55.99 cM	Chr5:114582330-114598652 (+) GRCm39		ENSMUSG00000041939 (Ensembl Gene Model) ENSMUSP00000107858 (Ensembl) ENSMUST00000112239 (Ensembl)
rat	Mvk	RGD:621295 (Rat Genome Database) 81727 (Entrez Gene) Mvk (Alliance of Genome Resources)	Chr12			P17256 (UniProt | EBI) NM_001393702 (RefSeq)
zebrafish	mvk	ZDB-GENE-041114-37 (Zebrafish Model Organism Database) 492477 (Entrez Gene) mvk (Alliance of Genome Resources)	Chr5			NP_001007350 (RefSeq) NM_001007349 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.