Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PLN	HGNC:9080 (HGNC) 5350 (Entrez Gene) 172405 (OMIM) PLN (Alliance of Genome Resources)	Chr6 q22.31	Chr6:118548296-118561716 (+) GRCh38	dilated cardiomyopathy 1P hypertrophic cardiomyopathy 18	P26678 (UniProt | EBI) NM_002667 (RefSeq)
mouse	Pln	MGI:97622 (MGI) 18821 (Entrez Gene) Gene Tree Pln (Alliance of Genome Resources)	Chr10 27.11 cM	Chr10:53213782-53222095 (+) GRCm39	centronuclear myopathy	18821 (NCBI Gene Model) P61014 (UniProt | EBI) NM_001141927 (RefSeq)
rat	Pln	RGD:619894 (Rat Genome Database) 64672 (Entrez Gene) Pln (Alliance of Genome Resources)	Chr20 q11			P61016 (UniProt | EBI) NM_022707 (RefSeq)
zebrafish	pln1	ZDB-GENE-060503-603 (Zebrafish Model Organism Database) 555548 (Entrez Gene) pln1 (Alliance of Genome Resources)	Chr20			NP_001188490 (RefSeq) NM_001201561 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.