Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PTHLH	HGNC:9607 (HGNC) 5744 (Entrez Gene) 168470 (OMIM) PTHLH (Alliance of Genome Resources)	Chr12 p11.22	Chr12:27958084-27972733 (-) GRCh38	brachydactyly type E2	P12272 (UniProt | EBI) NM_198966 (RefSeq)
mouse	Pthlh	MGI:97800 (MGI) 19227 (Entrez Gene) Gene Tree Pthlh (Alliance of Genome Resources)	Chr6 78.19 cM	Chr6:147153607-147165511 (-) GRCm39	achondroplasia Albright's hereditary osteodystrophy	19227 (NCBI Gene Model) P22858 (UniProt | EBI) NM_008970 (RefSeq)
rat	Pthlh	RGD:3441 (Rat Genome Database) 24695 (Entrez Gene) Pthlh (Alliance of Genome Resources)	Chr4 q44			P13085 (UniProt | EBI) NM_012636 (RefSeq)
zebrafish	pthlha	ZDB-GENE-050119-9 (Zebrafish Model Organism Database) 554221 (Entrez Gene) pthlha (Alliance of Genome Resources)	Chr4			NP_001019798 (RefSeq) NM_001024627 (RefSeq)
	pthlhb	ZDB-GENE-110411-206 (Zebrafish Model Organism Database) 751101 (Entrez Gene) pthlhb (Alliance of Genome Resources)	Chr25			NP_001036789 (RefSeq) NM_001043324 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.