Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MECOM	HGNC:3498 (HGNC) 2122 (Entrez Gene) 165215 (OMIM) MECOM (Alliance of Genome Resources)	Chr3 q26.2	Chr3:169083499-169663775 (-) GRCh38	myeloid neoplasm	Q03112 (UniProt | EBI) NM_001205194 (RefSeq)
mouse	Mecom	MGI:95457 (MGI) 14013 (Entrez Gene) Gene Tree Mecom (Alliance of Genome Resources)	Chr3 12.66 cM	Chr3:30005445-30563937 (-) GRCm39	otitis media	14013 (NCBI Gene Model) P14404 (UniProt | EBI) NM_001361034 (RefSeq)
rat	Mecom	RGD:1310997 (Rat Genome Database) 294924 (Entrez Gene) Mecom (Alliance of Genome Resources)	Chr2 q24			NP_001376211 (RefSeq) NM_001389282 (RefSeq)
zebrafish	mecom	ZDB-GENE-050208-123 (Zebrafish Model Organism Database) 497407 (Entrez Gene) mecom (Alliance of Genome Resources)	Chr15			XP_017206701 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.