Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NISCH	HGNC:18006 (HGNC) 11188 (Entrez Gene) 615507 (OMIM) NISCH (Alliance of Genome Resources)	Chr3 p21.1	Chr3:52455118-52493068 (+) GRCh38	congestive heart failure	Q9Y2I1 (UniProt | EBI) NM_001276293 (RefSeq)
mouse	Nisch	MGI:1928323 (MGI) 64652 (Entrez Gene) Gene Tree Nisch (Alliance of Genome Resources)	Chr14 19.09 cM	Chr14:30892885-30928783 (-) GRCm39	otitis media	64652 (NCBI Gene Model) Q80TM9 (UniProt | EBI) NM_022656 (RefSeq)
rat	Nisch	RGD:1306950 (Rat Genome Database) 306255 (Entrez Gene) Nisch (Alliance of Genome Resources)	Chr16 p16			Q4G017 (UniProt | EBI) NM_001409024 (RefSeq)
zebrafish	nisch	ZDB-GENE-050208-570 (Zebrafish Model Organism Database) 553087 (Entrez Gene) nisch (Alliance of Genome Resources)	Chr22			XP_002666276 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.