Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NKX2-2	HGNC:7835 (HGNC) 4821 (Entrez Gene) 604612 (OMIM) NKX2-2 (Alliance of Genome Resources)	Chr20 p11.22	Chr20:21511017-21522689 (-) GRCh38		O95096 (UniProt | EBI) NM_001424412 (RefSeq)
mouse	Nkx2-2	MGI:97347 (MGI) 18088 (Entrez Gene) Gene Tree Nkx2-2 (Alliance of Genome Resources)	Chr2 72.63 cM	Chr2:147019466-147036163 (-) GRCm39		ENSMUSG00000027434 (Ensembl Gene Model) ENSMUSP00000069666 (Ensembl) ENSMUST00000067075 (Ensembl)
rat	Nkx2-2	RGD:1308443 (Rat Genome Database) 366214 (Entrez Gene) Nkx2-2 (Alliance of Genome Resources)	Chr3 q41			NP_001178833 (RefSeq) NM_001191904 (RefSeq)
zebrafish	nkx2.2a	ZDB-GENE-980526-403 (Zebrafish Model Organism Database) 30697 (Entrez Gene) nkx2.2a (Alliance of Genome Resources)	Chr17			Q90481 (UniProt | EBI) NM_001308640 (RefSeq)
	nkx2.2b	ZDB-GENE-050217-3 (Zebrafish Model Organism Database) 493627 (Entrez Gene) nkx2.2b (Alliance of Genome Resources)	Chr20			NP_001007783 (RefSeq) NM_001007782 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.