DNMT3B Vertebrate HGNC

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Vertebrate Homology

Source

Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	DNMT3B	HGNC:2979 (HGNC) 1789 (Entrez Gene) 602900 (OMIM) DNMT3B (Alliance of Genome Resources)	Chr20 q11.21	Chr20:32762385-32809359 (+) GRCh38	acute myeloid leukemia autoimmune thrombocytopenic purpura colorectal adenocarcinoma facioscapulohumeral muscular dystrophy 4 head and neck squamous cell carcinoma immunodeficiency-centromeric instability-facial anomalies syndrome 1 lung adenocarcinoma lung small cell carcinoma oral squamous cell carcinoma rheumatoid arthritis schizophrenia thymoma	Q9UBC3 (UniProt \| EBI) NM_001424354 (RefSeq)
mouse	Dnmt3b	MGI:1261819 (MGI) 13436 (Entrez Gene) Gene Tree Dnmt3b (Alliance of Genome Resources)	Chr2 75.79 cM	Chr2:153491370-153529650 (+) GRCm39	immunodeficiency-centromeric instability-facial anomalies syndrome 1	ENSMUSG00000027478 (Ensembl Gene Model) ENSMUSP00000051830 (Ensembl) ENSMUST00000056495 (Ensembl)
rat	Dnmt3b	RGD:1303274 (Rat Genome Database) 444985 (Entrez Gene) Dnmt3b (Alliance of Genome Resources)	Chr3 q41			NP_001383278 (RefSeq) NM_001396349 (RefSeq)
zebrafish	dnmt3ba	ZDB-GENE-050314-4 (Zebrafish Model Organism Database) 321084 (Entrez Gene) dnmt3ba (Alliance of Genome Resources)	Chr8			NP_001018312 (RefSeq) NM_001020476 (RefSeq)
zebrafish	dnmt3bb.1	ZDB-GENE-050314-1 (Zebrafish Model Organism Database) 317744 (Entrez Gene) dnmt3bb.1 (Alliance of Genome Resources)	Chr23			NP_001020621 (RefSeq) NM_001025450 (RefSeq)