Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	XRCC3	HGNC:12830 (HGNC) 7517 (Entrez Gene) 600675 (OMIM) XRCC3 (Alliance of Genome Resources)	Chr14 q32.33	Chr14:103697609-103715504 (-) GRCh38	brain glioma breast cancer central nervous system cancer coronary artery disease familial melanoma high grade glioma hypertension meningioma multiple myeloma myocardial infarction pancreatic cancer	O43542 (UniProt | EBI) NM_005432 (RefSeq)
mouse	Xrcc3	MGI:1921585 (MGI) 74335 (Entrez Gene) Gene Tree Xrcc3 (Alliance of Genome Resources)	Chr12 61.14 cM	Chr12:111769626-111780307 (-) GRCm39		ENSMUSG00000021287 (Ensembl Gene Model) ENSMUSP00000021715 (Ensembl) ENSMUST00000021715 (Ensembl)
rat	Xrcc3	RGD:1306849 (Rat Genome Database) 102551085 (Entrez Gene) Xrcc3 (Alliance of Genome Resources)	Chr6			NP_001414349 (RefSeq) NM_001427420 (RefSeq)
zebrafish	xrcc3	ZDB-GENE-050320-116 (Zebrafish Model Organism Database) 541414 (Entrez Gene) xrcc3 (Alliance of Genome Resources)	Chr20			NP_001013559 (RefSeq) NM_001013541 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.