Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PARL	HGNC:18253 (HGNC) 55486 (Entrez Gene) 607858 (OMIM) PARL (Alliance of Genome Resources)	Chr3 q27.1		coronary artery disease hyperinsulinism Leber hereditary optic neuropathy myopia type 2 diabetes mellitus	Q9H300 (UniProt | EBI) NM_001324438 (RefSeq)
mouse	Parl	MGI:1277152 (MGI) 381038 (Entrez Gene) Gene Tree Parl (Alliance of Genome Resources)	Chr16 12.4 cM	Chr16:20098570-20121090 (-) GRCm39	Leigh disease	381038 (NCBI Gene Model) Q5XJY4 (UniProt | EBI) NM_001417573 (RefSeq)
rat	Parl	RGD:1306191 (Rat Genome Database) 287979 (Entrez Gene) Parl (Alliance of Genome Resources)	Chr11 q23			Q3B8P0 (UniProt | EBI) NM_001035249 (RefSeq)
zebrafish	parla	ZDB-GENE-050327-8 (Zebrafish Model Organism Database) 541485 (Entrez Gene) parla (Alliance of Genome Resources)	Chr2			Q58EK4 (UniProt | EBI) NM_001014298 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.