Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NMNAT1	HGNC:17877 (HGNC) 64802 (Entrez Gene) 608700 (OMIM) NMNAT1 (Alliance of Genome Resources)	Chr1 p36.22	Chr1:9942923-9996892 (+) GRCh38	Leber congenital amaurosis 9 spondyloepiphyseal dysplasia, sensorineural hearing loss, intellectual developmental disorder, and Leber congenital amaurosis	Q9HAN9 (UniProt | EBI) NM_001297779 (RefSeq)
mouse	Nmnat1	MGI:1913704 (MGI) 66454 (Entrez Gene) Gene Tree Nmnat1 (Alliance of Genome Resources)	Chr4 79.47 cM	Chr4:149552029-149569659 (-) GRCm39	Leber congenital amaurosis 9 retinal degeneration	ENSMUSG00000028992 (Ensembl Gene Model) ENSMUSP00000030845 (Ensembl) ENSMUST00000030845 (Ensembl)
rat	Nmnat1	RGD:1310996 (Rat Genome Database) 298653 (Entrez Gene) Nmnat1 (Alliance of Genome Resources)	Chr5 q36			NP_001032645 (RefSeq) NM_001037556 (RefSeq)
zebrafish	nmnat1	ZDB-GENE-050417-101 (Zebrafish Model Organism Database) 550322 (Entrez Gene) nmnat1 (Alliance of Genome Resources)	Chr23			NP_001315257 (RefSeq) NM_001328328 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.