Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	F3	HGNC:3541 (HGNC) 2152 (Entrez Gene) 134390 (OMIM) F3 (Alliance of Genome Resources)	Chr1 p21.3	Chr1:94529173-94541759 (-) GRCh38	B-lymphoblastic leukemia/lymphoma COVID-19 disseminated intravascular coagulation von Willebrand's disease	P13726 (UniProt | EBI) NM_001993 (RefSeq)
mouse	F3	MGI:88381 (MGI) 14066 (Entrez Gene) Gene Tree F3 (Alliance of Genome Resources)	Chr3 52.94 cM	Chr3:121517186-121528697 (+) GRCm39		ENSMUSG00000028128 (Ensembl Gene Model) ENSMUSP00000029771 (Ensembl) ENSMUST00000029771 (Ensembl)
rat	F3	RGD:2587 (Rat Genome Database) 25584 (Entrez Gene) F3 (Alliance of Genome Resources)	Chr2 q42			P42533 (UniProt | EBI) NM_013057 (RefSeq)
zebrafish	f3a	ZDB-GENE-071119-5 (Zebrafish Model Organism Database) 567257 (Entrez Gene) f3a (Alliance of Genome Resources)	Chr24			NP_001232896 (RefSeq) NM_001245967 (RefSeq)
	f3b	ZDB-GENE-050417-234 (Zebrafish Model Organism Database) 550423 (Entrez Gene) f3b (Alliance of Genome Resources)	Chr2			NP_001017728 (RefSeq) NM_001017728 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.