Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

 

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	AKR1B1	HGNC:381 (HGNC) 231 (Entrez Gene) 103880 (OMIM) AKR1B1 (Alliance of Genome Resources)	Chr7 q33	Chr7:134442350-134459284 (-) GRCh38	arteriosclerosis cataract diabetic neuropathy diabetic retinopathy type 2 diabetes mellitus	P15121 (UniProt | EBI) NM_001346142 (RefSeq)
mouse	Akr1b1	MGI:1353494 (MGI) 11677 (Entrez Gene) Gene Tree Akr1b1 (Alliance of Genome Resources)	Chr6 14.87 cM	Chr6:34280865-34294424 (-) GRCm39		11677 (NCBI Gene Model) P45376 (UniProt | EBI) NM_009658 (RefSeq)
rat	Akr1b1	RGD:2092 (Rat Genome Database) 24192 (Entrez Gene) Akr1b1 (Alliance of Genome Resources)	Chr4 q22			P07943 (UniProt | EBI) NM_012498 (RefSeq)
zebrafish	akr1b1.1	ZDB-GENE-040625-7 (Zebrafish Model Organism Database) 415138 (Entrez Gene) akr1b1.1 (Alliance of Genome Resources)	Chr4			NP_001002048 (RefSeq) NM_001002048 (RefSeq)
	akr1b1.2	ZDB-GENE-041210-132 (Zebrafish Model Organism Database) 553452 (Entrez Gene) akr1b1.2 (Alliance of Genome Resources)	Chr4			NP_001070715 (RefSeq) NM_001077247 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.