Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PTPN22	HGNC:9652 (HGNC) 26191 (Entrez Gene) 600716 (OMIM) PTPN22 (Alliance of Genome Resources)	Chr1 p13.2	Chr1:113813811-113871759 (-) GRCh38	Addison's disease alopecia areata autoimmune thrombocytopenic purpura autoimmune thyroiditis Behcet's disease chronic lymphocytic leukemia coronary artery disease Crohn's disease diabetes mellitus endometriosis graft-versus-host disease Graves' disease Graves ophthalmopathy hypothyroidism juvenile rheumatoid arthritis Meniere's disease myasthenia gravis psoriasis psoriatic arthritis pulmonary tuberculosis rheumatoid arthritis Sjogren's syndrome systemic lupus erythematosus systemic scleroderma temporal arteritis type 1 diabetes mellitus urticaria vitiligo	Q9Y2R2 (UniProt | EBI) NM_001308297 (RefSeq)
mouse	Ptpn22	MGI:107170 (MGI) 19260 (Entrez Gene) Gene Tree Ptpn22 (Alliance of Genome Resources)	Chr3 45.52 cM	Chr3:103767111-103819563 (+) GRCm39		ENSMUSG00000027843 (Ensembl Gene Model) ENSMUSP00000029433 (Ensembl) ENSMUST00000029433 (Ensembl)
rat	Ptpn22	RGD:1307992 (Rat Genome Database) 295338 (Entrez Gene) Ptpn22 (Alliance of Genome Resources)	Chr2 q34			NP_001099930 (RefSeq) NM_001106460 (RefSeq)
zebrafish	ptpn22	ZDB-GENE-060503-458 (Zebrafish Model Organism Database) 565606 (Entrez Gene) ptpn22 (Alliance of Genome Resources)	Chr23			NP_001092890 (RefSeq) NM_001099420 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.