Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	AKT3	HGNC:393 (HGNC) 10000 (Entrez Gene) 611223 (OMIM) AKT3 (Alliance of Genome Resources)	Chr1 q43-q44	Chr1:243488233-243851079 (-) GRCh38	colon cancer glioblastoma prostate adenocarcinoma prostate cancer renal cell carcinoma	Q9Y243 (UniProt | EBI) NM_001370074 (RefSeq)
mouse	Akt3	MGI:1345147 (MGI) 23797 (Entrez Gene) Gene Tree Akt3 (Alliance of Genome Resources)	Chr1 82.66 cM	Chr1:176847639-177085769 (-) GRCm39		ENSMUSG00000019699 (Ensembl Gene Model) ENSMUSP00000106789 (Ensembl) ENSMUST00000111159 (Ensembl)
rat	Akt3	RGD:62390 (Rat Genome Database) 29414 (Entrez Gene) Akt3 (Alliance of Genome Resources)	Chr13 q25			Q63484 (UniProt | EBI) NM_031575 (RefSeq)
zebrafish	akt3a	ZDB-GENE-050419-180 (Zebrafish Model Organism Database) 560549 (Entrez Gene) akt3a (Alliance of Genome Resources)	Chr13			NP_001184130 (RefSeq) NM_001197201 (RefSeq)
	akt3b	ZDB-GENE-110309-3 (Zebrafish Model Organism Database) 100149794 (Entrez Gene) akt3b (Alliance of Genome Resources)	Chr1			XP_001923454 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.