Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	WAS	HGNC:12731 (HGNC) 7454 (Entrez Gene) 300392 (OMIM) WAS (Alliance of Genome Resources)	ChrX p11.23	ChrX:48676596-48691431 (+) GRCh38	thrombocytopenia Wiskott-Aldrich syndrome X-linked severe congenital neutropenia	P42768 (UniProt | EBI) NM_000377 (RefSeq)
mouse	Was	MGI:105059 (MGI) 22376 (Entrez Gene) Gene Tree Was (Alliance of Genome Resources)	ChrX 3.65 cM	ChrX:7947705-7956730 (-) GRCm39	IgA glomerulonephritis Wiskott-Aldrich syndrome	22376 (NCBI Gene Model) P70315 (UniProt | EBI) NM_009515 (RefSeq)
rat	Was	RGD:1563567 (Rat Genome Database) 317371 (Entrez Gene) Was (Alliance of Genome Resources)	ChrX q12			NP_001385676 (RefSeq) NM_001398747 (RefSeq)
zebrafish	wasa	ZDB-GENE-081104-419 (Zebrafish Model Organism Database) 571256 (Entrez Gene) wasa (Alliance of Genome Resources)	Chr8			XP_699919 (RefSeq)
	wasb	ZDB-GENE-030131-7098 (Zebrafish Model Organism Database) 335158 (Entrez Gene) wasb (Alliance of Genome Resources)	Chr8			NP_956232 (RefSeq) NM_199938 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.