Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CLCN2	HGNC:2020 (HGNC) 1181 (Entrez Gene) 600570 (OMIM) CLCN2 (Alliance of Genome Resources)	Chr3 q27.1	Chr3:184346185-184361650 (-) GRCh38	idiopathic generalized epilepsy 11 primary hyperaldosteronism	P51788 (UniProt | EBI) NM_004366 (RefSeq)
mouse	Clcn2	MGI:105061 (MGI) 12724 (Entrez Gene) Gene Tree Clcn2 (Alliance of Genome Resources)	Chr16 12.5 cM	Chr16:20521714-20536496 (-) GRCm39	leukodystrophy primary hyperaldosteronism	ENSMUSG00000022843 (Ensembl Gene Model) ENSMUSP00000007207 (Ensembl) ENSMUST00000007207 (Ensembl)
rat	Clcn2	RGD:2361 (Rat Genome Database) 29232 (Entrez Gene) Clcn2 (Alliance of Genome Resources)	Chr11 q23			P35525 (UniProt | EBI) NM_017137 (RefSeq)
zebrafish	clcn2a	ZDB-GENE-070705-19 (Zebrafish Model Organism Database) 100150892 (Entrez Gene) clcn2a (Alliance of Genome Resources)	Chr2			NP_001315638 (RefSeq) NM_001328709 (RefSeq)
	clcn2b	ZDB-GENE-151006-1 (Zebrafish Model Organism Database) 100333644 (Entrez Gene) clcn2b (Alliance of Genome Resources)	ChrUN			NP_001303244 (RefSeq) NM_001316315 (RefSeq)
	clcn2c	ZDB-GENE-050506-73 (Zebrafish Model Organism Database) 563453 (Entrez Gene) clcn2c (Alliance of Genome Resources)	Chr15			NP_001306200 (RefSeq) NM_001319271 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.