Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ABCG2	HGNC:74 (HGNC) 9429 (Entrez Gene) 603756 (OMIM) ABCG2 (Alliance of Genome Resources)	Chr4 q22.1	Chr4:88090150-88231628 (-) GRCh38	B-cell lymphoma chronic myeloid leukemia gout multiple myeloma renal cell carcinoma toxic encephalopathy	Q9UNQ0 (UniProt | EBI) NM_001348989 (RefSeq)
mouse	Abcg2	MGI:1347061 (MGI) 26357 (Entrez Gene) Gene Tree Abcg2 (Alliance of Genome Resources)	Chr6 Syntenic	Chr6:58561476-58669436 (+) GRCm39	erythropoietic protoporphyria hyperuricemia	26357 (NCBI Gene Model) Q7TMS5 (UniProt | EBI) NM_011920 (RefSeq)
rat	Abcg2	RGD:631345 (Rat Genome Database) 312382 (Entrez Gene) Abcg2 (Alliance of Genome Resources)	Chr4 q24			Q80W57 (UniProt | EBI) NM_181381 (RefSeq)
zebrafish	abcg2a	ZDB-GENE-050517-35 (Zebrafish Model Organism Database) 735312 (Entrez Gene) abcg2a (Alliance of Genome Resources)	Chr23			NP_001036240 (RefSeq) NM_001042775 (RefSeq)
	abcg2d	ZDB-GENE-050517-38 (Zebrafish Model Organism Database) 735310 (Entrez Gene) abcg2d (Alliance of Genome Resources)	Chr1			NP_001036237 (RefSeq) NM_001042772 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.