Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ABCG8	HGNC:13887 (HGNC) 64241 (Entrez Gene) 605460 (OMIM) ABCG8 (Alliance of Genome Resources)	Chr2 p21	Chr2:43831942-43882988 (+) GRCh38	arteriosclerosis familial hyperlipidemia obesity sitosterolemia 1	Q9H221 (UniProt | EBI) NM_022437 (RefSeq)
mouse	Abcg8	MGI:1914720 (MGI) 67470 (Entrez Gene) Gene Tree Abcg8 (Alliance of Genome Resources)	Chr17 55.02 cM	Chr17:84983730-85007761 (+) GRCm39	sitosterolemia 1	67470 (NCBI Gene Model) Q9DBM0 (UniProt | EBI) NM_026180 (RefSeq)
rat	Abcg8	RGD:620300 (Rat Genome Database) 155192 (Entrez Gene) Abcg8 (Alliance of Genome Resources)	Chr6 q12			P58428 (UniProt | EBI) NM_130414 (RefSeq)
zebrafish	abcg8	ZDB-GENE-050517-41 (Zebrafish Model Organism Database) 100136850 (Entrez Gene) abcg8 (Alliance of Genome Resources)	Chr13			NP_001108041 (RefSeq) NM_001114569 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.