Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CAV3	HGNC:1529 (HGNC) 859 (Entrez Gene) 601253 (OMIM) CAV3 (Alliance of Genome Resources)	Chr3 p25.3	Chr3:8733802-8841808 (+) GRCh38	distal myopathy Tateyama type hypertrophic cardiomyopathy 1 isolated elevated serum creatine phosphokinase levels long QT syndrome 9 muscular dystrophy rippling muscle disease 2	P56539 (UniProt | EBI) NM_033337 (RefSeq)
mouse	Cav3	MGI:107570 (MGI) 12391 (Entrez Gene) Gene Tree Cav3 (Alliance of Genome Resources)	Chr6 52.26 cM	Chr6:112436466-112449833 (+) GRCm39	hypertrophic cardiomyopathy rippling muscle disease 2	12391 (NCBI Gene Model) P51637 (UniProt | EBI) NM_007617 (RefSeq)
rat	Cav3	RGD:2281 (Rat Genome Database) 29161 (Entrez Gene) Cav3 (Alliance of Genome Resources)	Chr4 q41			P51638 (UniProt | EBI) NM_019155 (RefSeq)
zebrafish	cav3	ZDB-GENE-050522-426 (Zebrafish Model Organism Database) 449679 (Entrez Gene) cav3 (Alliance of Genome Resources)	Chr6			NP_991301 (RefSeq) NM_205738 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.