Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CYP2E1	HGNC:2631 (HGNC) 1571 (Entrez Gene) 124040 (OMIM) CYP2E1 (Alliance of Genome Resources)	Chr10 q26.3	Chr10:133520406-133561220 (+) GRCh38	acoustic neuroma alcoholic liver cirrhosis chronic obstructive pulmonary disease colorectal cancer hepatocellular carcinoma high grade glioma liver disease nasopharynx carcinoma oral cavity cancer oral squamous cell carcinoma pneumonia steatotic liver disease stomach cancer	P05181 (UniProt | EBI) NM_000773 (RefSeq)
mouse	Cyp2e1	MGI:88607 (MGI) 13106 (Entrez Gene) Gene Tree Cyp2e1 (Alliance of Genome Resources)	Chr7 85.94 cM	Chr7:140343732-140354903 (+) GRCm39		13106 (NCBI Gene Model) Q05421 (UniProt | EBI) NM_021282 (RefSeq)
rat	Cyp2e1	RGD:2475 (Rat Genome Database) 25086 (Entrez Gene) Cyp2e1 (Alliance of Genome Resources)	Chr1 q41			P05182 (UniProt | EBI) NM_031543 (RefSeq)
zebrafish	cyp2y3	ZDB-GENE-050522-490 (Zebrafish Model Organism Database) 368352 (Entrez Gene) cyp2y3 (Alliance of Genome Resources)	Chr15			NP_001018658 (RefSeq) NM_001020822 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.