Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IL12B	HGNC:5970 (HGNC) 3593 (Entrez Gene) 161561 (OMIM) IL12B (Alliance of Genome Resources)	Chr5 q33.3	Chr5:159314780-159330863 (-) GRCh38	asthma chronic obstructive pulmonary disease immunodeficiency 29 salmonellosis	P29460 (UniProt | EBI) NM_002187 (RefSeq)
mouse	Il12b	MGI:96540 (MGI) 16160 (Entrez Gene) Gene Tree Il12b (Alliance of Genome Resources)	Chr11 25.94 cM	Chr11:44290890-44304860 (+) GRCm39		ENSMUSG00000004296 (Ensembl Gene Model) ENSMUSP00000099860 (Ensembl) ENSMUST00000102796 (Ensembl)
rat	Il12b	RGD:628704 (Rat Genome Database) 64546 (Entrez Gene) Il12b (Alliance of Genome Resources)	Chr10 q21			NP_072133 (RefSeq) NM_022611 (RefSeq)
zebrafish	il12ba	ZDB-GENE-050525-3 (Zebrafish Model Organism Database) 445373 (Entrez Gene) il12ba (Alliance of Genome Resources)	Chr14			NP_001007109 (RefSeq) NM_001007108 (RefSeq)
	il12bb	ZDB-GENE-030131-7937 (Zebrafish Model Organism Database) 335994 (Entrez Gene) il12bb (Alliance of Genome Resources)	Chr21			XP_068075079 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.