Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GJB1	HGNC:4283 (HGNC) 2705 (Entrez Gene) 304040 (OMIM) GJB1 (Alliance of Genome Resources)	ChrX q13.1	ChrX:71212811-71225516 (+) GRCh38	Charcot-Marie-Tooth disease X-linked dominant 1	P08034 (UniProt | EBI) NM_001097642 (RefSeq)
mouse	Gjb1	MGI:95719 (MGI) 14618 (Entrez Gene) Gene Tree Gjb1 (Alliance of Genome Resources)	ChrX 44.06 cM	ChrX:100419984-100429235 (+) GRCm39	Charcot-Marie-Tooth disease X-linked dominant 1	ENSMUSG00000047797 (Ensembl Gene Model) ENSMUSP00000113516 (Ensembl) ENSMUST00000119190 (Ensembl)
rat	Gjb1	RGD:61926 (Rat Genome Database) 29584 (Entrez Gene) Gjb1 (Alliance of Genome Resources)	ChrX q22			P08033 (UniProt | EBI) NM_017251 (RefSeq)
zebrafish	gjb1a	ZDB-GENE-010619-2 (Zebrafish Model Organism Database) 114405 (Entrez Gene) gjb1a (Alliance of Genome Resources)	Chr5			NP_571886 (RefSeq) NM_131811 (RefSeq)
	gjb1b	ZDB-GENE-050616-3 (Zebrafish Model Organism Database) 100150195 (Entrez Gene) gjb1b (Alliance of Genome Resources)	Chr14			NP_001373439 (RefSeq) NM_001386510 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.