Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	WFS1	HGNC:12762 (HGNC) 7466 (Entrez Gene) 606201 (OMIM) WFS1 (Alliance of Genome Resources)	Chr4 p16.1	Chr4:6269849-6303265 (+) GRCh38	autosomal dominant nonsyndromic deafness 6 autosomal dominant Wolfram syndrome cataract 41 diabetes mellitus diabetic retinopathy optic atrophy optic atrophy 1 sensorineural hearing loss type 1 diabetes mellitus type 2 diabetes mellitus Wolfram syndrome Wolfram syndrome 1	O76024 (UniProt | EBI) NM_001145853 (RefSeq)
mouse	Wfs1	MGI:1328355 (MGI) 22393 (Entrez Gene) Gene Tree Wfs1 (Alliance of Genome Resources)	Chr5 19.46 cM	Chr5:37123448-37146326 (-) GRCm39	nonsyndromic deafness Wolfram syndrome 1	22393 (NCBI Gene Model) P56695 (UniProt | EBI) NM_011716 (RefSeq)
rat	Wfs1	RGD:68954 (Rat Genome Database) 83725 (Entrez Gene) Wfs1 (Alliance of Genome Resources)	Chr14 q21			NP_114011 (RefSeq) NM_031823 (RefSeq)
zebrafish	wfs1a	ZDB-GENE-080225-11 (Zebrafish Model Organism Database) 566876 (Entrez Gene) wfs1a (Alliance of Genome Resources)	Chr1			XP_695252 (RefSeq)
	wfs1b	ZDB-GENE-050809-19 (Zebrafish Model Organism Database) 556580 (Entrez Gene) wfs1b (Alliance of Genome Resources)	Chr14			XP_684510 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.