Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MAGI2	HGNC:18957 (HGNC) 9863 (Entrez Gene) 606382 (OMIM) MAGI2 (Alliance of Genome Resources)	Chr7 q21.11	Chr7:78017055-79453667 (-) GRCh38	nephrotic syndrome type 15	Q86UL8 (UniProt | EBI) NM_001301128 (RefSeq)
mouse	Magi2	MGI:1354953 (MGI) 50791 (Entrez Gene) Gene Tree Magi2 (Alliance of Genome Resources)	Chr5 8.6 cM	Chr5:19432034-20909790 (+) GRCm39	schizophrenia	ENSMUSG00000040003 (Ensembl Gene Model) ENSMUSP00000142576 (Ensembl) ENSMUST00000197354 (Ensembl)
rat	Magi2	RGD:621855 (Rat Genome Database) 113970 (Entrez Gene) Magi2 (Alliance of Genome Resources)	Chr4 q11			O88382 (UniProt | EBI) NM_053621 (RefSeq)
zebrafish	magi2a	ZDB-GENE-050810-4 (Zebrafish Model Organism Database) 564112 (Entrez Gene) magi2a (Alliance of Genome Resources)	Chr4			NP_001314782 (RefSeq) NM_001327853 (RefSeq)
	magi2b	ZDB-GENE-141211-6 (Zebrafish Model Organism Database) 100001810 (Entrez Gene) magi2b (Alliance of Genome Resources)	Chr25			XP_068075228 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.