Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	BCL2	HGNC:990 (HGNC) 596 (Entrez Gene) 151430 (OMIM) BCL2 (Alliance of Genome Resources)	Chr18 q21.33	Chr18:63123346-63320128 (-) GRCh38	acute myeloid leukemia esophagus adenocarcinoma follicular lymphoma intracranial aneurysm lung small cell carcinoma plasmacytoma prostate cancer renal cell carcinoma retinal degeneration transitional cell carcinoma urinary bladder cancer	P10415 (UniProt | EBI) NM_000633 (RefSeq)
mouse	Bcl2	MGI:88138 (MGI) 12043 (Entrez Gene) Gene Tree Bcl2 (Alliance of Genome Resources)	Chr1 49.76 cM	Chr1:106465908-106642004 (-) GRCm39	oligomeganephronia	ENSMUSG00000057329 (Ensembl Gene Model) ENSMUSP00000108371 (Ensembl) ENSMUST00000112751 (Ensembl)
rat	Bcl2	RGD:2199 (Rat Genome Database) 24224 (Entrez Gene) Bcl2 (Alliance of Genome Resources)	Chr13 p11			P49950 (UniProt | EBI) NM_016993 (RefSeq)
zebrafish	bcl2a	ZDB-GENE-051012-1 (Zebrafish Model Organism Database) 570772 (Entrez Gene) bcl2a (Alliance of Genome Resources)	Chr24			NP_001025424 (RefSeq) NM_001030253 (RefSeq)
	bcl2b	ZDB-GENE-110411-185 (Zebrafish Model Organism Database) 100007048 (Entrez Gene) bcl2b (Alliance of Genome Resources)	Chr2			XP_001341214 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.