Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IL11	HGNC:5966 (HGNC) 3589 (Entrez Gene) 147681 (OMIM) IL11 (Alliance of Genome Resources)	Chr19 q13.42	Chr19:55364382-55370463 (-) GRCh38		P20809 (UniProt | EBI) NM_001267718 (RefSeq)
mouse	Il11	MGI:107613 (MGI) 16156 (Entrez Gene) Gene Tree Il11 (Alliance of Genome Resources)	Chr7 2.76 cM	Chr7:4775372-4785858 (-) GRCm39		ENSMUSG00000004371 (Ensembl Gene Model) ENSMUSP00000092492 (Ensembl) ENSMUST00000094892 (Ensembl)
rat	Il11	RGD:621475 (Rat Genome Database) 171040 (Entrez Gene) Il11 (Alliance of Genome Resources)	Chr1 q12			Q99MF5 (UniProt | EBI) NM_133519 (RefSeq)
zebrafish	il11a	ZDB-GENE-051019-1 (Zebrafish Model Organism Database) 570404 (Entrez Gene) il11a (Alliance of Genome Resources)	Chr16			XP_698974 (RefSeq)
	il11b	ZDB-GENE-051019-2 (Zebrafish Model Organism Database) 108180095 (Entrez Gene) il11b (Alliance of Genome Resources)	Chr19			XP_021323960 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.