Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TCF21	HGNC:11632 (HGNC) 6943 (Entrez Gene) 603306 (OMIM) TCF21 (Alliance of Genome Resources)	Chr6 q23.2	Chr6:133889113-133895553 (+) GRCh38	coronary artery disease ventricular septal defect	O43680 (UniProt | EBI) NM_198392 (RefSeq)
mouse	Tcf21	MGI:1202715 (MGI) 21412 (Entrez Gene) Gene Tree Tcf21 (Alliance of Genome Resources)	Chr10 10.33 cM	Chr10:22693162-22696042 (-) GRCm39		21412 (NCBI Gene Model) O35437 (UniProt | EBI) NM_011545 (RefSeq)
rat	Tcf21	RGD:620523 (Rat Genome Database) 252856 (Entrez Gene) Tcf21 (Alliance of Genome Resources)	Chr1 p12			NP_001027569 (RefSeq) NM_001032397 (RefSeq)
zebrafish	tcf21	ZDB-GENE-051113-88 (Zebrafish Model Organism Database) 558148 (Entrez Gene) tcf21 (Alliance of Genome Resources)	Chr23			Q32PV5 (UniProt | EBI) NM_001037681 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.