Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CACNA1S	HGNC:1397 (HGNC) 779 (Entrez Gene) 114208 (OMIM) CACNA1S (Alliance of Genome Resources)	Chr1 q32.1	Chr1:201039512-201112451 (-) GRCh38	congenital myopathy 18 hypokalemic periodic paralysis malignant hyperthermia	Q13698 (UniProt | EBI) NM_000069 (RefSeq)
mouse	Cacna1s	MGI:88294 (MGI) 12292 (Entrez Gene) Gene Tree Cacna1s (Alliance of Genome Resources)	Chr1 59.55 cM	Chr1:135980549-136047268 (+) GRCm39	hypokalemic periodic paralysis	12292 (NCBI Gene Model) Q02789 (UniProt | EBI) NM_001081023 (RefSeq)
rat	Cacna1s	RGD:70983 (Rat Genome Database) 682930 (Entrez Gene) Cacna1s (Alliance of Genome Resources)	Chr13			Q02485 (UniProt | EBI) NM_053873 (RefSeq)
zebrafish	cacna1sa	ZDB-GENE-090514-1 (Zebrafish Model Organism Database) 570683 (Entrez Gene) cacna1sa (Alliance of Genome Resources)	Chr22			NP_001139622 (RefSeq) NM_001146150 (RefSeq)
	cacna1sb	ZDB-GENE-051227-1 (Zebrafish Model Organism Database) 405791 (Entrez Gene) cacna1sb (Alliance of Genome Resources)	Chr8			NP_999891 (RefSeq) NM_214726 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.