Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	RIPPLY2	HGNC:21390 (HGNC) 134701 (Entrez Gene) 609891 (OMIM) RIPPLY2 (Alliance of Genome Resources)	Chr6 q14.2	Chr6:83853229-83857515 (+) GRCh38	spondylocostal dysostosis 6	Q5TAB7 (UniProt | EBI) NM_001400899 (RefSeq)
mouse	Ripply2	MGI:2685968 (MGI) 382089 (Entrez Gene) Gene Tree Ripply2 (Alliance of Genome Resources)	Chr9 46.69 cM	Chr9:86897590-86901970 (+) GRCm39	spondylocostal dysostosis	ENSMUSG00000047897 (Ensembl Gene Model) ENSMUSP00000055369 (Ensembl) ENSMUST00000058846 (Ensembl)
rat	Ripply2	RGD:1308746 (Rat Genome Database) 363111 (Entrez Gene) Ripply2 (Alliance of Genome Resources)	Chr8 q31			NP_001385671 (RefSeq) NM_001398742 (RefSeq)
zebrafish	ripply1	ZDB-GENE-060113-1 (Zebrafish Model Organism Database) 654446 (Entrez Gene) ripply1 (Alliance of Genome Resources)	Chr21			Q2WG80 (UniProt | EBI) NM_001039108 (RefSeq)
	ripply2	ZDB-GENE-060113-2 (Zebrafish Model Organism Database) 654447 (Entrez Gene) ripply2 (Alliance of Genome Resources)	Chr4			Q2WG79 (UniProt | EBI) NM_001039109 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.