Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	KMT2D	HGNC:7133 (HGNC) 8085 (Entrez Gene) 602113 (OMIM) KMT2D (Alliance of Genome Resources)	Chr12 q13.12	Chr12:49018975-49060794 (-) GRCh38	esophagus squamous cell carcinoma gastric adenocarcinoma intracranial aneurysm Kabuki syndrome lung non-small cell carcinoma lung small cell carcinoma lung squamous cell carcinoma papillary thyroid carcinoma	O14686 (UniProt | EBI) NM_003482 (RefSeq)
mouse	Kmt2d	MGI:2682319 (MGI) 381022 (Entrez Gene) Gene Tree Kmt2d (Alliance of Genome Resources)	Chr15 Syntenic	Chr15:98729550-98769085 (-) GRCm39	Kabuki syndrome	ENSMUSG00000048154 (Ensembl Gene Model) ENSMUSP00000135941 (Ensembl) ENSMUST00000178486 (Ensembl)
zebrafish	kmt2d	ZDB-GENE-060223-2 (Zebrafish Model Organism Database) 100536523 (Entrez Gene) kmt2d (Alliance of Genome Resources)	Chr23			XP_017209162 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.