Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NUMB	HGNC:8060 (HGNC) 8650 (Entrez Gene) 603728 (OMIM) NUMB (Alliance of Genome Resources)	Chr14 q24.2-q24.3	Chr14:73275107-73458617 (-) GRCh38		P49757 (UniProt | EBI) NM_001320114 (RefSeq)
mouse	Numb	MGI:107423 (MGI) 18222 (Entrez Gene) Gene Tree Numb (Alliance of Genome Resources)	Chr12 38.89 cM	Chr12:83840808-83968708 (-) GRCm39		18222 (NCBI Gene Model) Q9QZS3 (UniProt | EBI) NM_001411949 (RefSeq)
rat	Numb	RGD:620107 (Rat Genome Database) 29419 (Entrez Gene) Numb (Alliance of Genome Resources)	Chr6 q31			Q2LC84 (UniProt | EBI) NM_001411954 (RefSeq)
zebrafish	numb	ZDB-GENE-060422-1 (Zebrafish Model Organism Database) 692064 (Entrez Gene) numb (Alliance of Genome Resources)	Chr17			NP_001035496 (RefSeq) NM_001040406 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.