Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	KMT2B	HGNC:15840 (HGNC) 9757 (Entrez Gene) 606834 (OMIM) KMT2B (Alliance of Genome Resources)	Chr19 q13.12	Chr19:35717973-35738880 (+) GRCh38	autosomal dominant intellectual developmental disorder colorectal adenocarcinoma dystonia 28, childhood-onset hepatocellular carcinoma	Q9UMN6 (UniProt | EBI) NM_014727 (RefSeq)
mouse	Kmt2b	MGI:109565 (MGI) 75410 (Entrez Gene) Gene Tree Kmt2b (Alliance of Genome Resources)	Chr7 18.63 cM	Chr7:30268283-30288151 (-) GRCm39		ENSMUSG00000006307 (Ensembl Gene Model) ENSMUSP00000006470 (Ensembl) ENSMUST00000006470 (Ensembl)
rat	Kmt2b	RGD:7678027 (Rat Genome Database) 102550344 (Entrez Gene) Kmt2b (Alliance of Genome Resources)	Chr1			NP_001414070 (RefSeq) NM_001427141 (RefSeq)
zebrafish	kmt2ba	ZDB-GENE-060503-376 (Zebrafish Model Organism Database) 560856 (Entrez Gene) kmt2ba (Alliance of Genome Resources)	Chr19			XP_689347 (RefSeq)
	kmt2bb	ZDB-GENE-080521-1 (Zebrafish Model Organism Database) 566825 (Entrez Gene) kmt2bb (Alliance of Genome Resources)	Chr15			XP_002664717 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.