Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NPR1	HGNC:7943 (HGNC) 4881 (Entrez Gene) 108960 (OMIM) NPR1 (Alliance of Genome Resources)	Chr1 q21.3	Chr1:153678688-153693992 (+) GRCh38	myocardial infarction	P16066 (UniProt | EBI) NM_000906 (RefSeq)
mouse	Npr1	MGI:97371 (MGI) 18160 (Entrez Gene) Gene Tree Npr1 (Alliance of Genome Resources)	Chr3 39.23 cM	Chr3:90357898-90373173 (-) GRCm39		ENSMUSG00000027931 (Ensembl Gene Model) ENSMUSP00000029540 (Ensembl) ENSMUST00000029540 (Ensembl)
rat	Npr1	RGD:3195 (Rat Genome Database) 24603 (Entrez Gene) Npr1 (Alliance of Genome Resources)	Chr2 q34			P18910 (UniProt | EBI) NM_012613 (RefSeq)
zebrafish	npr1a	ZDB-GENE-060503-539 (Zebrafish Model Organism Database) 560653 (Entrez Gene) npr1a (Alliance of Genome Resources)	Chr19			NP_001038402 (RefSeq) NM_001044937 (RefSeq)
	npr1b	ZDB-GENE-100805-4 (Zebrafish Model Organism Database) 555911 (Entrez Gene) npr1b (Alliance of Genome Resources)	Chr16			XP_009290669 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.