Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NPHP4	HGNC:19104 (HGNC) 261734 (Entrez Gene) 607215 (OMIM) NPHP4 (Alliance of Genome Resources)	Chr1 p36.31	Chr1:5862811-5992473 (-) GRCh38	congenital heart disease Joubert syndrome 4 nephronophthisis nephronophthisis 4 Senior-Loken syndrome	O75161 (UniProt | EBI) NM_015102 (RefSeq)
mouse	Nphp4	MGI:2384210 (MGI) 260305 (Entrez Gene) Gene Tree Nphp4 (Alliance of Genome Resources)	Chr4 83.14 cM	Chr4:152561163-152647640 (+) GRCm39	nephronophthisis 4	ENSMUSG00000039577 (Ensembl Gene Model) ENSMUSP00000049920 (Ensembl) ENSMUST00000056567 (Ensembl)
rat	Nphp4	RGD:1560172 (Rat Genome Database) 313749 (Entrez Gene) Nphp4 (Alliance of Genome Resources)	Chr5 q36			NP_001032739 (RefSeq) NM_001037650 (RefSeq)
zebrafish	nphp4	ZDB-GENE-060503-715 (Zebrafish Model Organism Database) 560234 (Entrez Gene) nphp4 (Alliance of Genome Resources)	Chr8			XP_021327729 (RefSeq) NM_001130775 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.