Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FANCA	HGNC:3582 (HGNC) 2175 (Entrez Gene) 607139 (OMIM) FANCA (Alliance of Genome Resources)	Chr16 q24.3	Chr16:89726683-89816977 (-) GRCh38	acute myeloid leukemia breast cancer cervical cancer esophagus squamous cell carcinoma Fanconi anemia Fanconi anemia complementation group A ovarian cancer pancreatic cancer primary ovarian insufficiency skin melanoma urinary bladder cancer	O15360 (UniProt | EBI) NM_001351830 (RefSeq)
mouse	Fanca	MGI:1341823 (MGI) 14087 (Entrez Gene) Gene Tree Fanca (Alliance of Genome Resources)	Chr8 72.1 cM	Chr8:123995039-124045315 (-) GRCm39	Fanconi anemia complementation group A	ENSMUSG00000032815 (Ensembl Gene Model) ENSMUSP00000045217 (Ensembl) ENSMUST00000035495 (Ensembl)
rat	Fanca	RGD:1311380 (Rat Genome Database) 361435 (Entrez Gene) Fanca (Alliance of Genome Resources)	Chr19 q12			NP_001388181 (RefSeq) NM_001401252 (RefSeq)
zebrafish	fanca	ZDB-GENE-060508-1 (Zebrafish Model Organism Database) 692125 (Entrez Gene) fanca (Alliance of Genome Resources)	ChrUN			NP_001035725 (RefSeq) NM_001040635 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.