Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SETBP1	HGNC:15573 (HGNC) 26040 (Entrez Gene) 611060 (OMIM) SETBP1 (Alliance of Genome Resources)	Chr18 q12.3	Chr18:44680073-45068510 (+) GRCh38	autosomal dominant intellectual developmental disorder 29 Schinzel Giedion syndrome	Q9Y6X0 (UniProt | EBI) NM_001130110 (RefSeq)
mouse	Setbp1	MGI:1933199 (MGI) 240427 (Entrez Gene) Gene Tree Setbp1 (Alliance of Genome Resources)	Chr18 52.67 cM	Chr18:78793595-79152606 (-) GRCm39		ENSMUSG00000024548 (Ensembl Gene Model) ENSMUSP00000025430 (Ensembl) ENSMUST00000025430 (Ensembl)
rat	Setbp1	RGD:1306229 (Rat Genome Database) 291423 (Entrez Gene) Setbp1 (Alliance of Genome Resources)	Chr18 q12.3			NP_001414555 (RefSeq) NM_001427626 (RefSeq)
zebrafish	setbp1	ZDB-GENE-060526-72 (Zebrafish Model Organism Database) 796785 (Entrez Gene) setbp1 (Alliance of Genome Resources)	Chr5			XP_005165732 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.