Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SPINK2	HGNC:11245 (HGNC) 6691 (Entrez Gene) 605753 (OMIM) SPINK2 (Alliance of Genome Resources)	Chr4 q12	Chr4:56809860-56821869 (-) GRCh38	spermatogenic failure 29	P20155 (UniProt | EBI) NM_001271721 (RefSeq)
mouse	Spink2	MGI:1917232 (MGI) 69982 (Entrez Gene) Gene Tree Spink2 (Alliance of Genome Resources)	Chr5 41.53 cM	Chr5:77352954-77359318 (-) GRCm39		ENSMUSG00000053030 (Ensembl Gene Model) ENSMUSP00000067117 (Ensembl) ENSMUST00000065216 (Ensembl)
rat	Spink2	RGD:1302956 (Rat Genome Database) 408234 (Entrez Gene) Spink2 (Alliance of Genome Resources)	Chr14 p11			Q6IE49 (UniProt | EBI) NM_001008870 (RefSeq)
zebrafish	spink2.1	ZDB-GENE-070112-972 (Zebrafish Model Organism Database) 565497 (Entrez Gene) spink2.1 (Alliance of Genome Resources)	Chr14			NP_001185680 (RefSeq) NM_001198751 (RefSeq)
	spink2.2	ZDB-GENE-141216-292 (Zebrafish Model Organism Database) 100537783 (Entrez Gene) spink2.2 (Alliance of Genome Resources)	Chr14			NP_001373436 (RefSeq) NM_001386507 (RefSeq)
	spink2.3	ZDB-GENE-141216-190 (Zebrafish Model Organism Database) 101882741 (Entrez Gene) spink2.3 (Alliance of Genome Resources)	Chr14			XP_005157264 (RefSeq)
	spink2.4	ZDB-GENE-141216-194 (Zebrafish Model Organism Database) 100537980 (Entrez Gene) spink2.4 (Alliance of Genome Resources)	Chr14			XP_003199924 (RefSeq)
	spink2.5	ZDB-GENE-141216-182 (Zebrafish Model Organism Database) 100538065 (Entrez Gene) spink2.5 (Alliance of Genome Resources)	Chr14			NP_001373551 (RefSeq) NM_001386622 (RefSeq)
	spink2.6	ZDB-GENE-141216-334 (Zebrafish Model Organism Database) 108192106 (Entrez Gene) spink2.6 (Alliance of Genome Resources)	Chr14
	spink2.7	ZDB-GENE-091118-100 (Zebrafish Model Organism Database) 100537819 (Entrez Gene) spink2.7 (Alliance of Genome Resources)	Chr14			NP_001373549 (RefSeq) NM_001386620 (RefSeq)
	spink2.8	ZDB-GENE-141216-151 (Zebrafish Model Organism Database) 100537943 (Entrez Gene) spink2.8 (Alliance of Genome Resources)	Chr14			NP_001373478 (RefSeq) NM_001386549 (RefSeq)
	spink2.9	ZDB-GENE-141216-159 (Zebrafish Model Organism Database) 100538025 (Entrez Gene) spink2.9 (Alliance of Genome Resources)	Chr14			NP_001373550 (RefSeq) NM_001386621 (RefSeq)
	spink2.10	ZDB-GENE-141216-169 (Zebrafish Model Organism Database) 100537905 (Entrez Gene) spink2.10 (Alliance of Genome Resources)	Chr14			NP_001373480 (RefSeq) NM_001386551 (RefSeq)
	spink2.11	ZDB-GENE-141216-153 (Zebrafish Model Organism Database) 100537859 (Entrez Gene) spink2.11 (Alliance of Genome Resources)	Chr14			NP_001373519 (RefSeq) NM_001386590 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.