Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	THRA	HGNC:11796 (HGNC) 7067 (Entrez Gene) 190120 (OMIM) THRA (Alliance of Genome Resources)	Chr17 q21.1	Chr17:40058290-40093867 (+) GRCh38	congenital nongoitrous hypothyroidism 6 renal cell carcinoma	P10827 (UniProt | EBI) NM_003250 (RefSeq)
mouse	Thra	MGI:98742 (MGI) 21833 (Entrez Gene) Gene Tree Thra (Alliance of Genome Resources)	Chr11 62.58 cM	Chr11:98631539-98659832 (+) GRCm39	thyroid hormone resistance syndrome	21833 (NCBI Gene Model) P63058 (UniProt | EBI) NM_001313983 (RefSeq)
rat	Thra	RGD:3857 (Rat Genome Database) 81812 (Entrez Gene) Thra (Alliance of Genome Resources)	Chr10 q31			P63059 (UniProt | EBI) NM_001017960 (RefSeq)
zebrafish	thraa	ZDB-GENE-990415-263 (Zebrafish Model Organism Database) 30670 (Entrez Gene) thraa (Alliance of Genome Resources)	Chr3			Q98867 (UniProt | EBI) NM_131396 (RefSeq)
	thrab	ZDB-GENE-060613-1 (Zebrafish Model Organism Database) 558427 (Entrez Gene) thrab (Alliance of Genome Resources)	Chr12			XP_001921013 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.