Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TLK2	HGNC:11842 (HGNC) 11011 (Entrez Gene) 608439 (OMIM) TLK2 (Alliance of Genome Resources)	Chr17 q23.2	Chr17:62458658-62615481 (+) GRCh38	autosomal dominant intellectual developmental disorder	Q86UE8 (UniProt | EBI) NM_006852 (RefSeq)
mouse	Tlk2	MGI:1346023 (MGI) 24086 (Entrez Gene) Gene Tree Tlk2 (Alliance of Genome Resources)	Chr11 68.61 cM	Chr11:105069633-105174785 (+) GRCm39		ENSMUSG00000020694 (Ensembl Gene Model) ENSMUSP00000102554 (Ensembl) ENSMUST00000106941 (Ensembl)
rat	Tlk2	RGD:1310907 (Rat Genome Database) 303592 (Entrez Gene) Tlk2 (Alliance of Genome Resources)	Chr10 q32.1			NP_001178581 (RefSeq) NM_001191652 (RefSeq)
zebrafish	tlk2	ZDB-GENE-060623-36 (Zebrafish Model Organism Database) 407732 (Entrez Gene) tlk2 (Alliance of Genome Resources)	Chr3			Q1ECX4 (UniProt | EBI) NM_001110417 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.