Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GCK	HGNC:4195 (HGNC) 2645 (Entrez Gene) 138079 (OMIM) GCK (Alliance of Genome Resources)	Chr7 p13	Chr7:44143213-44198170 (-) GRCh38	coronary artery disease diabetes mellitus familial hyperinsulinemic hypoglycemia 3 gestational diabetes hyperinsulinism hypertension hypoglycemia maturity-onset diabetes of the young type 2 permanent neonatal diabetes mellitus type 2 diabetes mellitus	P35557 (UniProt | EBI) NM_033508 (RefSeq)
mouse	Gck	MGI:1270854 (MGI) 103988 (Entrez Gene) Gene Tree Gck (Alliance of Genome Resources)	Chr11 3.88 cM	Chr11:5850820-5900081 (-) GRCm39	familial hyperinsulinemic hypoglycemia 3 hyperinsulinemic hypoglycemia maturity-onset diabetes of the young type 2 type 2 diabetes mellitus	ENSMUSG00000041798 (Ensembl Gene Model) ENSMUSP00000105447 (Ensembl) ENSMUST00000109822 (Ensembl)
rat	Gck	RGD:2670 (Rat Genome Database) 24385 (Entrez Gene) Gck (Alliance of Genome Resources)	Chr14 q21			P17712 (UniProt | EBI) NM_001270850 (RefSeq)
zebrafish	gck	ZDB-GENE-060825-204 (Zebrafish Model Organism Database) 751668 (Entrez Gene) gck (Alliance of Genome Resources)	Chr8			NP_001038850 (RefSeq) NM_001045385 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.