Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SPI1	HGNC:11241 (HGNC) 6688 (Entrez Gene) 165170 (OMIM) SPI1 (Alliance of Genome Resources)	Chr11 p11.2	Chr11:47354860-47409369 (-) GRCh38	agammaglobulinemia 10	P17947 (UniProt | EBI) NM_001080547 (RefSeq)
mouse	Spi1	MGI:98282 (MGI) 20375 (Entrez Gene) Gene Tree Spi1 (Alliance of Genome Resources)	Chr2 50.44 cM	Chr2:90912750-90946104 (+) GRCm39	acute myeloid leukemia	20375 (NCBI Gene Model) P17433 (UniProt | EBI) NM_011355 (RefSeq)
rat	Spi1	RGD:1359607 (Rat Genome Database) 366126 (Entrez Gene) Spi1 (Alliance of Genome Resources)	Chr3 q24			Q6BDS1 (UniProt | EBI) NM_001005892 (RefSeq)
zebrafish	spi1a	ZDB-GENE-060825-351 (Zebrafish Model Organism Database) 751704 (Entrez Gene) spi1a (Alliance of Genome Resources)	Chr25			NP_001417886 (RefSeq) NM_001045416 (RefSeq)
	spi1b	ZDB-GENE-980526-164 (Zebrafish Model Organism Database) 30117 (Entrez Gene) spi1b (Alliance of Genome Resources)	Chr7			NP_001315297 (RefSeq) NM_001328368 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.