Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HLF	HGNC:4977 (HGNC) 3131 (Entrez Gene) 142385 (OMIM) HLF (Alliance of Genome Resources)	Chr17 q22	Chr17:55264960-55325187 (+) GRCh38		Q16534 (UniProt | EBI) NM_001330375 (RefSeq)
mouse	Hlf	MGI:96108 (MGI) 217082 (Entrez Gene) Gene Tree Hlf (Alliance of Genome Resources)	Chr11 55.03 cM	Chr11:90227362-90281721 (-) GRCm39		ENSMUSG00000003949 (Ensembl Gene Model) ENSMUSP00000004051 (Ensembl) ENSMUST00000004051 (Ensembl)
rat	Hlf	RGD:1582828 (Rat Genome Database) 690286 (Entrez Gene) Hlf (Alliance of Genome Resources)	Chr10 q26			Q64709 (UniProt | EBI) NM_001100764 (RefSeq)
zebrafish	hlfa	ZDB-GENE-061013-159 (Zebrafish Model Organism Database) 768192 (Entrez Gene) hlfa (Alliance of Genome Resources)	Chr3			NP_001070802 (RefSeq) NM_001077334 (RefSeq)
	hlfb	ZDB-GENE-110420-3 (Zebrafish Model Organism Database) 557886 (Entrez Gene) hlfb (Alliance of Genome Resources)	Chr12			NP_001183988 (RefSeq) NM_001197059 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.